Purpose To compare the effectiveness of mixed reality with traditional manikin-based simulation in basic life support (BLS) training, testing the hypothesis that mixed reality is non-inferior to manikin-based simulation.
Methods A non-inferiority randomized controlled trial was conducted. Third-year medical students were randomized into 2 groups. The mixed reality group received 32 minutes of individual training using a virtual reality headset and a torso for chest compressions (CC). The manikin group participated in 2 hours of group training consisting of theoretical and practical sessions using a low-fidelity manikin. The primary outcome was the overall BLS performance score, assessed at 1 month through a standardized BLS scenario using a 10-item assessment scale. The quality of CC, student satisfaction, and confidence levels were secondary outcomes and assessed through superiority analyses.
Results Data from 155 participants were analyzed, with 84 in the mixed reality group and 71 in the manikin group. The mean overall BLS performance score was 6.4 (mixed reality) vs. 6.5 (manikin), (mean difference, –0.1; 95% confidence interval [CI], –0.45 to +∞). CC depth was greater in the manikin group (50.3 mm vs. 46.6 mm; mean difference, –3.7 mm; 95% CI, –6.5 to –0.9), with 61.2% achieving optimal depth compared to 43.8% in the mixed reality group (mean difference, 17.4%; 95% CI, –29.3 to –5.5). Satisfaction was higher in the mixed reality group (4.9/5 vs. 4.7/5 in the manikin group; difference, 0.2; 95% CI, 0.07 to 0.33), as was confidence in performing BLS (3.9/5 vs. 3.6/5; difference, 0.3; 95% CI, 0.11 to 0.58). No other significant differences were observed for secondary outcomes.
Conclusion Mixed reality is non-inferior to manikin simulation in terms of overall BLS performance score assessed at 1 month.
Citations
Citations to this article as recorded by
Enhancing virtual reality applications for adult basic life support: insights from a comparative analysis Nino Fijačko, Benjamin S. Abella, Vinay M. Nadkarni, Špela Metličar, Anne-Astrid Agten, Robert Greif Virtual Reality.2026;[Epub] CrossRef
Enhancing STEM and STEAM Education at the Grade Level Through Mixed Reality Applications: A Meta-analytical Study Segun Michael Ojetunde, Umesh Ramnarain Canadian Journal of Science, Mathematics and Technology Education.2026;[Epub] CrossRef
Collocated mixed reality for basic life support training in medical students: a randomised pilot feasibility trial David Maiershon, Jonathan Giron, Vered Daitch, Yael Feinstein, Hadas Leibovich-Kot, Shlomit Tovbis, Tohar Levartovsky Ovadiya, Hadar Lavi, Ben Hazan, Maxim Lantsman, Alon Basker, Miri Mizrahi Reuveni Resuscitation Plus.2026; : 101383. CrossRef
IMPACTOS DO USO DE SIMULAÇÃO IMERSIVA NA CAPACITAÇÃO EM ATENDIMENTO À PARADA CARDIORRESPIRATÓRIA Iago Brenner Farias Leal, Izabelly Ferreira de Andrade, Yan Carlos de Sousa Diniz, Lara Maria Ferreira Lopes Valéri Pinto, Maria Helena Vieira Pereira Marques, Francisca Evelyn Abreu de Lira, Thaís Helena Gomes de Sousa, Maria Isabelly Araújo Ferreira, A Revista Multidisciplinar do Nordeste Mineiro.2025; 16(1): 1. CrossRef