Skip Navigation
Skip to contents

JEEHP : Journal of Educational Evaluation for Health Professions


Author index

Page Path
HOME > Browse articles > Author index
Jung Tae Kim 1 Article
Guidelines for the management of extravasation  
Jung Tae Kim, Jeong Yun Park, Hyun Jung Lee, Young Ju Cheon
J Educ Eval Health Prof. 2020;17:21.   Published online August 10, 2020
  • 15,068 View
  • 681 Download
  • 18 Citations
AbstractAbstract PDFSupplementary Material
The purpose of these practice guidelines is to offer and share strategies for preventing extravasation and measures for handling drugs known to cause tissue necrosis, which may occur even with the most skilled experts at intravenous (IV) injection. Herein, general knowledge about extravasation is first described, including its definition, incidence, risk factors, diagnosis, differential diagnosis, and extravasation injuries. Management of extravasation includes nursing intervention and thermal application. At the first sign of extravasation, nursing intervention with following steps is recommended: stop administration of IV fluids immediately, disconnect the IV tube from the cannula, aspirate any remaining drug from the cannula, administer drug-specific antidote, and notify the physician. Local thermal treatments are used to decrease the site reaction and absorption of the infiltrate. Local cooling (ice packs) aids in vasoconstriction, theoretically limiting the drug dispersion. Although clear benefit has not been demonstrated with thermal applications, it remains a standard supportive care. The recommended application schedule for both warm and cold applications is 15 to 20 minutes, every 4 hours, for 24 to 48 hours. For prevention of extravasation, health professionals should be familiar with the extravasation management standard guidelines. They should regularly check the extravasation kit, assess patients’ sensory changes, tingling or burning, and always pay attention to patients’ words. The medical team’s continuous education on extravasation is essential. With the practical use of these guidelines, it is expected to reduce the occurrence rate of extravasation and contribute to patient care improvement.


Citations to this article as recorded by  
  • Peripheral venous extravasation injury
    M.J. Billingham, R. Mittal
    BJA Education.2023; 23(2): 42.     CrossRef
  • Cutaneous Management after Extravasation of High-Concentrated Amino Acid Solution Administered for Renal Protection in PRRT
    Chaninart Sakulpisuti, Wichana Chamroonrat, Supatporn Tepmongkol
    Tomography.2022; 8(1): 356.     CrossRef
  • An updated narrative review on the management of the most common oncological and hematological emergencies
    Ali Issani
    Disease-a-Month.2022; : 101355.     CrossRef
  • SOP Einteilung und Therapie von Paravasaten
    Svenja Wulf
    Onkologie up2date.2022; 4(02): 116.     CrossRef
  • Effectiveness of structured teaching programme on knowledge regarding management of extravasation of chemotherapeutic drugs
    Prakash Pooja, Chandra Ayush , Kotha Malathi , Das Santosh Kumar , Prakash Barsha , Chandra Avinash , Sherpa Gyaljin , Acharya Sudikshya
    Insights on the Depression and Anxiety.2022; 6(1): 018.     CrossRef
  • Intervenção de enfermagem perante o extravasamento de citostáticos - um contributo na prevenção da queimadura química
    Ana Marcelino, Marta Ganhão
    Onco.News.2022; (45): e067.     CrossRef
  • Yenidoğan yoğun bakım ünitesinde çalışan sağlık personelinin ekstravazasyon bilgi birikimi ve yönetimi
    Ayşen ORMAN, Yalçın ÇELİK, Nihan ÖZEL ERÇEL
    Mersin Üniversitesi Sağlık Bilimleri Dergisi.2022; : 465.     CrossRef
  • SOP Einteilung und Therapie von Paravasaten
    Svenja Wulf
    Frauenheilkunde up2date.2021; 15(02): 107.     CrossRef
  • Tissue distribution of epirubicin after severe extravasation in humans
    Jakob Nedomansky, Werner Haslik, Ursula Pluschnig, Christoph Kornauth, Christine Deutschmann, Stefan Hacker, Günther G. Steger, Rupert Bartsch, Robert M. Mader
    Cancer Chemotherapy and Pharmacology.2021; 88(2): 203.     CrossRef
  • Novel Conformal Skin Patch with Embedded Thin-Film Electrodes for Early Detection of Extravasation
    Ruiqi Lim, Ramona B. Damalerio, Choon Looi Bong, Swee Kim Tan, Ming-Yuan Cheng
    Sensors.2021; 21(10): 3429.     CrossRef
  • Efficacy of combination of localized closure, ethacridine lactate dressing, and phototherapy in treatment of severe extravasation injuries: A case series
    Yan-Xu Lu, Ying Wu, Peng-Fei Liang, Rong-Chan Wu, Ling-Yun Tian, Hui-Ying Mo
    World Journal of Clinical Cases.2021; 9(18): 4599.     CrossRef
  • Modern approaches for long-term venous access in oncology
    Yu.V. Buydenok
    Onkologiya. Zhurnal imeni P.A.Gertsena.2021; 10(3): 69.     CrossRef
  • Elaboration and validation of an algorithm for treating peripheral intravenous infiltration and extravasation in children
    Luciano Marques dos Santos, Katharinne de Jesus Nunes, Cleonara Sousa Gomes e Silva, Denise Miyuki Kusahara, Elisa da Conceição Rodrigues, Ariane Ferreira Machado Avelar
    Revista Latino-Americana de Enfermagem.2021;[Epub]     CrossRef
  • Measuring the Validity and Reliability of the Vascular Access Complication Staging and Treatment Instrument in a Pediatric Population
    Genieveve J. Cline, Virginia Pohlod, Kristina J. Burger, Ernest K. Amankwah
    Journal of Infusion Nursing.2021; 44(4): 225.     CrossRef
  • Nurses’ knowledge and experience related to short peripheral venous catheter extravasation
    Selma Atay, Şengül Üzen Cura, Sevda Efil
    The Journal of Vascular Access.2021; : 112972982110455.     CrossRef
  • Chemotherapy Extravasation: Incidence of and Factors Associated With Events in a Community Cancer Center
    Nancy Ehmke
    Clinical Journal of Oncology Nursing.2021; 25(6): 680.     CrossRef
  • Drug Extravasation in a Large General Hospital in Hunan, China: A Retrospective Survey
    Zhihong Gong, Jinghui Zhang, Jianmei Hou, Shujie Chen, Zixin Hu, Xiaoya Kong, Guiyuan Ma, Lingxia Luo
    Risk Management and Healthcare Policy.2021; Volume 14: 4931.     CrossRef
  • The Journal Citation Indicator has arrived for Emerging Sources Citation Index journals, including the Journal of Educational Evaluation for Health Professions, in June 2021
    Sun Huh
    Journal of Educational Evaluation for Health Professions.2021; 18: 20.     CrossRef

JEEHP : Journal of Educational Evaluation for Health Professions